20. GENERAL PHARMACOLOGY (МIII-ОФАР)
STUDY PROGRAM
DEPARTMENT
COURSE TITLE / CODE
COURSE STATUS
INTEGRATED STUDIES IN MEDICINE
DEPARTMENT OF PHARMACOLOGY, TOXICOLOGY AND CLINICAL PHARMACOLOGY
GENERAL PHARMACOLOGY
COMPULSORY
Condition: MEDICAL BIOCHEMISTRY AND CHEMISTRY; PHYSIOLOGY (exam)
Year of
study
Winter semester (hours/week)
III
Summer semester (hours/week)
Lecture
Practice
Lecture
Practice
0
0
3
1
Teaching methods
Colloquia
Seminars
2
ECTS
Credits
4,5
Lectures, Practical work
AIM
Medical students are acquainted with basic biologic mechanisms of drugs and their effects on organ systems
Knowledge
GOAL
Skills
Student should know why, how and when to apply particular drug, general information on drug
metabolism in the body, site and mechanism of its action, interactions and side effects of drugs. Student
must be able to describe the effects, therapeutic indications and application of drugs used in treatment of
microbial diseases.
Practical classes deal with practical pharmacotherapeutical problems and recipes. Student must know to:
• to properly fill a prescription (magistral drugs, officinal drugs, ready-made drugs) and to explain it;
• to use drug register books;
• to fill the registration form / report on unwanted effects of the drug.
Theoretical classes
SADRŽAJ PREDMETA
History of Pharmacology. The drug and the poison.
Mode of application. Dosage of drugs. Doses. Therapeutic index and therapeutic scope of the drug.
Movement of the drug in the body. Biomembrane penetration. Reabsorption and distribution of drugs.
Excretion of drugs.
Drug metabolism. Induction and enzyme inhibition. Factors affecting the metabolism of drugs.
Pharmacokinetic models. Pharmacokinetic parameters.
Drug action. Sites of action. Mechanisms of action. Receptors. G-protein.
Interactions of drugs. Synergism and antagonism. Applying drugs in particular circumstances (children,
elderly, pathological condition, pregnancy, breastfeeding).
Pharmacogenetics
Adverse effects of drugs. Addiction.
Toxicology. Poisons. Drug poisoning.
Disinfection and antisepsis.
Antimicrobial agents.
Antimycotic, antiviral and antiparasitic drugs
Practical classes
Drug classification. Putting drugs on the market. Names of drugs.
Pharmacopoeia. Drug prescription scheme. Magistral and generic formulas. Ready-made drugs.
Drugs in solid form.
Drugs in liquid form.
Semi-solid forms of drugs.
Inhalation.
Bandage material.
Antimicrobial drug prescription.
1.
2.
3.
4.
Compulsory
5.
RECOMMENDED
LITERATURE
6.
1.
2.
3.
Optional
4.
5.
Varagić V, Milošević M. FARMAKOLOGIJA. Elit Medica, Beograd (2004., 2005.,
2006. ili 2007.)
Sabo A, Tomić Z, Stanulović M. ANTIBAKTERIJSKI LEKOVI. A.D.Š. Kultura, Bački
Petrovac, 2001.
Vasović V, Mikov M, Đaković-Švajcer K. ODABRANA POGLAVLjA IZ
TOKSIKOLOGIJE. Štamparija Borac, Kula, 2003.
Đaković-Švajcer K and sar. TEST-PITANjA IZ FARMAKOLOGIJE and
TOKSIKOLOGIJE. Medicinski fakultet Novi Sad, 2001.
Popović J, Sabo A, Mikov M. PRIRUČNIK IZ FARMAKOLOGIJE,
TOKSIKOLOGIJE and KLINIČKE FARMAKOLOGIJE-OPŠTI DEO. Nova prosveta,
1992.
Mikov M, Popović J, Sabo A. PRIRUČNIK IZ FARMAKOLOGIJE,
TOKSIKOLOGIJE and KLINIČKE FARMAKOLOGIJE-SPECIJALNI DEO. Nova
prosveta, 1992.
Rang HP, Dale MM, Ritter JM, Moore PK. FARMAKOLOGIJA. Data Status, Beograd,
2005.
Joksović D. AKUTNA TROVANjA LEKOVIMA. Rivel, Beograd, 1999.
Popović
J.
MATEMATIČKI
PRINCIPI
U
FARMAKOKINETICI,
KOMPARTMANSKOJ ANALIZI and BIOFARMACIJI. Medicinski fakultet Novi Sad,
1999.
Stanojević Z, Bukumirić Z, Bulajić S. FARMAKOGRAFIJA ZA STUDENTE
MEDICINE. Alfagraf, Petrovaradin, 2007.
LEKOVI U PROMETU, OrtoMedics, Novi Sad, 2007 (i starija izdanja)
Student’s activity assessment (points)
Pre-exam activities
Lecture
Practice
Colloquium
20
2h20
Total
Final exam
Essay
Other
Pismeni
Oral
10
30
100
Teaching staff
Techn.
1
1.
2.
3.
4.
5.
6.
Teaching Ass.
Lecturer
3
Prof dr Kornelija Đaković-Švajcer
Prof. dr Ana Sabo
Prof. dr Momir Mikov
Prof. dr Jovan Popović
Prof. dr Zdenko Tomić
Doc. dr Velibor Vasović
Assist.Prof.
3
7.
8.
9.
10.
11.
Assoc.Prof.
Full-time Prof.
4
Doc. dr Aleksandar Rašković
Teaching Ass. mr Isidora Samojlik
Teaching Ass. mr Olga Horvat
Teaching Ass. mr Saša Vukmirović
Techn. demonstrator Boris Milijašević, dr
Head of the Department
Prof. dr Ana Sabo. s.r.
Scient. Res.
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20. GENERAL PHARMACOLOGY (МIII-ОФАР)