IV Международная конференция «ЭОС–2010»
5-С39.
INVESTIGATION FOR THE EFFECT OF EXTRACTS ISOLATED
FROM (BRASSICA NAPUS SSP. OLEIFERA) (KANOLA-KOLZA)
SPECIES ON REPLICATION OF RAT HEPATOCYTES
Yeşim Kara, Ramazan Mammadov, Merve Parlak,
Özgün Teksoy, Mahmut Yıldıztekin
Pamukkale University,Faculty of Science and Arts.,
Department of Biology, Kınıklı-Denizli,Turlkey
[email protected]
B. napus ssp. oleifera L. oil is rich of vitamin E and has an
important antoxidant effect in reducing the risk of chronic cardiac
diseases. The studies were carried out on rats. At the core of this
study, there is a surgical operation carried out on the liver. To this
end, the rats were classified into two groups.
From these groups, one of them is control group, the other one
is first and second group upon which the studies were led. As a
result of the resection, certain amount of the rat liver is taken, being
cut. The hepatosit loses of operation results fulfilled on rats are 50%
respectively.
Immediately after the hepatic tissue is taken, the rats were
kept alive, stitching their abdominal region. The surgical operation
was fulfilled in Pamukkale University Medical Science Faculty
Experimental Research Unit. Generally hepatosit replication is
treated by apoptosis method. Therefore, this study is led by the
extractions got out of. B. napus ssp. oleifera L. species (%0,5 and %
1 concentration).
The liver enzymes of ALT, AST, GGT, which were regularly
taken from cardiac area during six weeks, and UREA rate, whose
variation in blood could be observed in the kidney functions, were
altogether taken into consideration. At the end of this study, a
statistically significant decrease was demonstrated in ALT and
UREA values in the control group, group I as result of hepatic
dissection.
259
Download

IV Международная конференция «ЭОС–2010» 5